The researchers analyzed the presence of glycosaminoglycans, molecules which can be associated to the presence of 14 completely different types of cancer.
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6 Dec 2022 – 2:51 p.m
(Updated at 2:52 pm)
The new technique can be utilized in folks at excessive danger of cancer, over the age of 55 or with a household historical past
Photo: Viện Huyết học – Truyến mội Trung ương / Pixabay
The large drawback of Cancer It is tough to acknowledge them within the early phases. However, an evaluation referred to as “liquid biopsy” was carried out as properly blood take a look atyou can Find 14 completely different typesSecond Study Published this Monday (5) within the journal PNAS. This is a crucial place to begin for detecting the illness non-invasively.
With urine and blood samples from 1,260 volunteers, the researchers analyzed the presence of glycosaminoglycans, that’s, molecules associated to the presence of 14 completely different types of cancer. As a outcome, the sensitivity for detecting tumors by blood elevated from 10% to 62%, and the accuracy of tumor location was 89%.
In phrases of price, it can price round R$ 50, which is between 5 and ten instances the worth of a liquid biopsy immediately.
The research’s lead writer, Francisco Gatto, a researcher on the Karolinska Institute in Sweden, informed the newspaper El Payson that there are nonetheless some steps left for the tactic to achieve laboratories and clinics.
According to Gatto, an evaluation like this can even be mixed with a take a look at for the presence of tumor DNA within the blood.
Photo: Fernando Ximinicella / Pixbe
“The subsequent step is to pattern greater than 10,000 members to guage the situation through which it makes extra sense to make use of this technique and, earlier than it’s accredited for the detection of many types of cancer, a bigger research might be wanted, with 100 thousand members”, he says. is
Who ought to take the take a look at and potential mixtures
But the take a look at will not be proper for everybody. Such screening would make extra sense in folks “at excessive danger of cancer, over age 55, or with a household historical past of cancer,” in accordance with the researcher.
An evaluation like this can even be mixed with testing for the presence of tumor DNA within the blood earlier than signs seem. He argues: “The identical blood pattern can be used to check for glycosaminoglycans and genetic markers. This mixture could also be ample to be a singular diagnostic system”.
Gatto based Ellipta to make sure the accessibility of liquid biopsies to detect early-stage cancers. The firm has already raised 21 million euros in funding. If the mission goes forward, the cancer mortality fee may very well be diminished to fifteen%, in accordance with research figures from the corporate Grail, which additionally focuses on liquid biopsies.
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